secobarbital will lower the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. Consider a rise in cannabidiol dosage (based upon clinical response and tolerability) when coadministered with a robust CYP3A4 inducer.
secobarbital will reduce the level or effect of alprazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
secobarbital will lessen the level or effect of ethinylestradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. The efficacy of hormonal contraceptives may be reduced. Use of a nonhormonal contraceptive is recommended.
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secobarbital will lessen the extent or effect of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by increasing metabolism. Contraindicated. Powerful CYP2C8 inducers could reduce dasabuvir stages, and for that reason lessened efficacy of Viekira Pak
Seconal is known to get addictive. This is the higher risk with Continual use or when used in almost any way other than prescribed by a doctor.
secobarbital will lower the level or effect of doxorubicin liposomal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
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These kinds of conclusions have emerged over the training course of treatment with sedative-hypnotic drugs. Due to the fact a number of the vital adverse effects of sedative-hypnotics appear to be dose relevant (see PRECAUTIONS and DOSAGE AND ADMINISTRATION), it is vital to use the smallest feasible effective dose, especially in the elderly.
secobarbital will decrease the extent or effect of methadone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
secobarbital will lower the extent or effect of buprenorphine subdermal implant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Watch individuals currently on buprenorphine subdermal implant who have to have freshly-initiated treatment with CYP3A4 inducer for signs and symptoms of withdrawal.
In sufferers with hepatic damage, barbiturates need to be administered with caution and originally in reduced doses. Barbiturates really should not be administered to people exhibiting the premonitory indications of hepatic coma.
secobarbital will lower the extent or effect of etravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
Seconal Sodium (secobarbital sodium capsules) capsules are orange and imprinted with RX679 on both the cap and the body: